GB1525762A – Quaternary ammonium polymers
– Google Patents
GB1525762A – Quaternary ammonium polymers
– Google Patents
Quaternary ammonium polymers
Info
Publication number
GB1525762A
GB1525762A
GB15642/76A
GB1564276A
GB1525762A
GB 1525762 A
GB1525762 A
GB 1525762A
GB 15642/76 A
GB15642/76 A
GB 15642/76A
GB 1564276 A
GB1564276 A
GB 1564276A
GB 1525762 A
GB1525762 A
GB 1525762A
Authority
GB
United Kingdom
Prior art keywords
polymers
reacted
end groups
aqueous solution
chloropropyl
Prior art date
1975-04-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB15642/76A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1975-04-23
Filing date
1976-04-15
Publication date
1978-09-20
1976-04-15
Application filed by Merck and Co Inc
filed
Critical
Merck and Co Inc
1978-09-20
Publication of GB1525762A
publication
Critical
patent/GB1525762A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 – C08G71/00
C08G73/02—Polyamines
C08G73/0206—Polyalkylene(poly)amines
C08G73/0213—Preparatory process
C08G73/0226—Quaternisation of polyalkylene(poly)amines
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
C07C209/74—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton by halogenation, hydrohalogenation, dehalogenation, or dehydrohalogenation
Abstract
1525762 Quaternary ammonium polymers MERCK & CO Inc 15 April 1976 [23 April 1975] 15642/76 Heading C3R The invention comprises polymers of formula and their acid addition salts, where W is propyl, 3-halopropyl, 3-hydroxypropyl, allyl, trialkylammoniopropyl (associated with an anion Y) or RSCH 2 CH 2 CH 2 -, R being alkyl, phenyl or naphthyl, Y is pharmaceutically acceptable anion, a is the anionic charge on Y, m is such that the product of m and a is 1, n is such that the polymer has a molecular weight above 2000. The polymers where W is -CH 2 CH 2 CH 2 X (X being chlorine, bromine or iodine) are obtained by heating an aqueous solution of a compound of formula These polymers then may be reacted with appropriate materials to replace the halogen atom and obtain the polymers where W has the other meanings listed above. In examples 3-[N
GB15642/76A
1975-04-23
1976-04-15
Quaternary ammonium polymers
Expired
GB1525762A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
US05/570,910
US4016209A
(en)
1975-04-23
1975-04-23
3-[N’-(3-Halopropyl)-N-‘-methylamino]-N,N,N-trimethyl-1-propanaminium halide and acid addition salts thereof
Publications (1)
Publication Number
Publication Date
GB1525762A
true
GB1525762A
(en)
1978-09-20
Family
ID=24281556
Family Applications (2)
Application Number
Title
Priority Date
Filing Date
GB43741/77A
Expired
GB1539006A
(en)
1975-04-23
1976-04-15
Aminoalkylammonium compound
GB15642/76A
Expired
GB1525762A
(en)
1975-04-23
1976-04-15
Quaternary ammonium polymers
Family Applications Before (1)
Application Number
Title
Priority Date
Filing Date
GB43741/77A
Expired
GB1539006A
(en)
1975-04-23
1976-04-15
Aminoalkylammonium compound
Country Status (29)
Country
Link
US
(3)
US4016209A
(en)
JP
(1)
JPS51136605A
(en)
AR
(1)
AR223301A1
(en)
AT
(1)
AT354099B
(en)
AU
(1)
AU506771B2
(en)
BE
(1)
BE841005A
(en)
CA
(1)
CA1082228A
(en)
CS
(1)
CS190529B2
(en)
DD
(2)
DD131564A5
(en)
DE
(1)
DE2617524A1
(en)
DK
(1)
DK164576A
(en)
EG
(1)
EG12656A
(en)
ES
(1)
ES447059A1
(en)
FI
(1)
FI760939A
(en)
FR
(2)
FR2308375A1
(en)
GB
(2)
GB1539006A
(en)
GR
(1)
GR59848B
(en)
HU
(1)
HU175963B
(en)
IE
(1)
IE44097B1
(en)
IL
(1)
IL49392A
(en)
LU
(1)
LU74759A1
(en)
NL
(1)
NL7603653A
(en)
NO
(1)
NO761208L
(en)
NZ
(1)
NZ180581A
(en)
PH
(1)
PH14726A
(en)
PL
(1)
PL113974B1
(en)
PT
(1)
PT65031B
(en)
SE
(1)
SE7604094L
(en)
ZA
(1)
ZA762407B
(en)
Families Citing this family (33)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4093657A
(en)
*
1976-04-09
1978-06-06
Merck & Co., Inc.
Process for preparing monomer of bile acid sequestrant polymer
FR2356425A1
(en)
*
1976-07-01
1978-01-27
Roussel Uclaf
APPLICATION AS MEDICINAL PRODUCTS FROM ORGANIC DERIVATIVES OF MONTMORILLONITE
US4185088A
(en)
*
1977-02-17
1980-01-22
Merck & Co., Inc.
Non-adhesive ionene quaternary polymer compositions useful as bile acid sequestrants
NZ191762A
(en)
*
1978-10-19
1982-09-14
Merck & Co Inc
Hypocholesteremic composition containing cholesterol synthesis inhibitor and anion exchange resin
IT1185484B
(en)
*
1985-10-31
1987-11-12
Pirelli Cavi Spa
ELECTRIC CABLE AND MATERIAL FOR COATING ELECTRICAL CONDUCTORS WITH THE FUNCTION OF INSULATOR AND / OR SHEATH
US4824602A
(en)
*
1986-10-27
1989-04-25
The Procter & Gamble Company
Processes for purification of quaternary cationic surfactant materials and cosmetic compositions containing same
US5349089A
(en)
*
1989-07-07
1994-09-20
National Starch And Chemical Investment Holding Corporation
Reagent for preparing polycationic polysaccharides
US6129910A
(en)
*
1993-06-02
2000-10-10
Geltex Pharmaceuticals, Inc.
Water-insoluble noncrosslinked bile acid sequestrants
US5618530A
(en)
*
1994-06-10
1997-04-08
Geltex Pharmaceuticals, Inc.
Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5929184A
(en)
*
1993-06-02
1999-07-27
Geltex Pharmaceuticals, Inc.
Hydrophilic nonamine-containing and amine-containing copolymers and their use as bile acid sequestrants
US5624963A
(en)
*
1993-06-02
1997-04-29
Geltex Pharmaceuticals, Inc.
Process for removing bile salts from a patient and compositions therefor
US5900475A
(en)
*
1994-06-10
1999-05-04
Geltex Pharmaceuticals, Inc.
Hydrophobic sequestrant for cholesterol depletion
US5607669A
(en)
*
1994-06-10
1997-03-04
Geltex Pharmaceuticals, Inc.
Amine polymer sequestrant and method of cholesterol depletion
US5703188A
(en)
*
1993-06-02
1997-12-30
Geltex Pharmaceuticals, Inc.
Process for removing bile salts from a patient and compositions therefor
US5667775A
(en)
1993-08-11
1997-09-16
Geltex Pharmaceuticals, Inc.
Phosphate-binding polymers for oral administration
US5496545A
(en)
*
1993-08-11
1996-03-05
Geltex Pharmaceuticals, Inc.
Phosphate-binding polymers for oral administration
TW474813B
(en)
*
1994-06-10
2002-02-01
Geltex Pharma Inc
Alkylated composition for removing bile salts from a patient
WO1996021454A1
(en)
*
1995-01-12
1996-07-18
Geltex Pharmaceuticals, Inc.
Phosphate-binding polymers for oral administration
CN1108801C
(en)
*
1995-01-12
2003-05-21
吉尔特药品公司
Phosphate-binding polymers for oral administration
US20040053208A1
(en)
*
1995-08-29
2004-03-18
V. I. TECHNOLOGIES, Inc.
Methods to selectively inactivate parasites in biological compositions
US6203785B1
(en)
1996-12-30
2001-03-20
Geltex Pharmaceuticals, Inc.
Poly(diallylamine)-based bile acid sequestrants
GB2321900A
(en)
*
1997-02-11
1998-08-12
Procter & Gamble
Cationic surfactants
US6423754B1
(en)
1997-06-18
2002-07-23
Geltex Pharmaceuticals, Inc.
Method for treating hypercholesterolemia with polyallylamine polymers
US6093564A
(en)
*
1997-10-03
2000-07-25
V.I. Technologies, Inc.
Methods and compositions for the selective modification of nucleic acids
US6352695B1
(en)
1997-10-03
2002-03-05
V.I. Technologies, Inc.
Methods and compositions for the selective modification of nucleic acids
US6726905B1
(en)
1997-11-05
2004-04-27
Genzyme Corporation
Poly (diallylamines)-based phosphate binders
US6403359B1
(en)
1998-09-25
2002-06-11
V. I. TECHNOLOGIES, Inc.
Solid phase quenching systems
US6617100B2
(en)
1998-09-25
2003-09-09
V.I. Technologies, Inc.
Solid phase quenching systems
US6733780B1
(en)
1999-10-19
2004-05-11
Genzyme Corporation
Direct compression polymer tablet core
US7985418B2
(en)
2004-11-01
2011-07-26
Genzyme Corporation
Aliphatic amine polymer salts for tableting
EP1951266A2
(en)
2005-09-02
2008-08-06
Genzyme Corporation
Method for removing phosphate and polymer used therefore
EP3000460A1
(en)
2005-09-15
2016-03-30
Genzyme Corporation
Sachet formulation for amine polymers
MA41202A
(en)
2014-12-18
2017-10-24
Genzyme Corp
CROSS-LINKED POLYDIALLYMINE COPOLYMERS FOR THE TREATMENT OF TYPE 2 DIABETES
Family Cites Families (14)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US2163181A
(en)
*
1935-03-01
1939-06-20
Ig Farbenindustrie Ag
Process of producing halogen-alkyl amines or their salts
US2884057A
(en)
*
1954-02-25
1959-04-28
American Cyanamid Co
Paper of improved dry strength and method of making same
US3147065A
(en)
*
1960-05-02
1964-09-01
Minnesota Mining & Mfg
Quaternized halomethylamides
US3234150A
(en)
*
1960-06-16
1966-02-08
Nalco Chemical Co
Strong base anion exchange resins from polymeric tertiary amines
AT252890B
(en)
*
1961-02-07
1967-03-10
American Cyanamid Co
Process for the production of new hydroxydiamines
NL282900A
(en)
*
1961-09-22
1900-01-01
US3372129A
(en)
*
1964-10-06
1968-03-05
Nalco Chemical Co
Method of preparing polyamines
US3370048A
(en)
*
1965-03-15
1968-02-20
Eastman Kodak Co
Process for the preparation of new linear condensation polymers
CH508583A
(en)
*
1968-01-31
1971-06-15
Bayer Ag
Process for the preparation of 3-aminopropanols
US3493615A
(en)
*
1968-10-28
1970-02-03
Colgate Palmolive Co
Surfactant anti-microbial compounds
NL7103340A
(en)
*
1970-03-19
1971-09-21
US3632507A
(en)
*
1970-06-30
1972-01-04
Standard Brands Chem Ind Inc
Flocculation of particles dispersed in aqueous media and flocculants used therein
CH553284A
(en)
*
1971-03-15
1974-08-30
CH568958A5
(en)
*
1972-04-28
1975-11-14
Sandoz Ag
1975
1975-04-23
US
US05/570,910
patent/US4016209A/en
not_active
Expired – Lifetime
1976
1976-04-07
SE
SE7604094A
patent/SE7604094L/en
not_active
Application Discontinuation
1976-04-07
FI
FI760939A
patent/FI760939A/fi
not_active
Application Discontinuation
1976-04-07
NL
NL7603653A
patent/NL7603653A/en
not_active
Application Discontinuation
1976-04-07
DK
DK164576A
patent/DK164576A/en
unknown
1976-04-08
NO
NO761208A
patent/NO761208L/no
unknown
1976-04-12
NZ
NZ180581A
patent/NZ180581A/en
unknown
1976-04-12
IL
IL49392A
patent/IL49392A/en
unknown
1976-04-13
GR
GR50537A
patent/GR59848B/en
unknown
1976-04-14
AU
AU12991/76A
patent/AU506771B2/en
not_active
Expired
1976-04-14
CA
CA250,746A
patent/CA1082228A/en
not_active
Expired
1976-04-14
ES
ES447059A
patent/ES447059A1/en
not_active
Expired
1976-04-14
LU
LU74759A
patent/LU74759A1/xx
unknown
1976-04-15
GB
GB43741/77A
patent/GB1539006A/en
not_active
Expired
1976-04-15
GB
GB15642/76A
patent/GB1525762A/en
not_active
Expired
1976-04-16
FR
FR7611409A
patent/FR2308375A1/en
active
Granted
1976-04-16
CS
CS762547A
patent/CS190529B2/en
unknown
1976-04-20
AR
AR262931A
patent/AR223301A1/en
active
1976-04-20
EG
EG233/76A
patent/EG12656A/en
active
1976-04-21
IE
IE832/76A
patent/IE44097B1/en
unknown
1976-04-21
DD
DD7600192453A
patent/DD131564A5/en
unknown
1976-04-21
PL
PL1976188926A
patent/PL113974B1/en
unknown
1976-04-21
DD
DD7600199971A
patent/DD131645A5/en
unknown
1976-04-21
AT
AT290976A
patent/AT354099B/en
not_active
IP Right Cessation
1976-04-22
ZA
ZA762407A
patent/ZA762407B/en
unknown
1976-04-22
DE
DE19762617524
patent/DE2617524A1/en
not_active
Withdrawn
1976-04-22
PT
PT65031A
patent/PT65031B/en
unknown
1976-04-22
HU
HU76ME1968A
patent/HU175963B/en
unknown
1976-04-22
BE
BE166369A
patent/BE841005A/en
unknown
1976-04-23
JP
JP51045650A
patent/JPS51136605A/en
active
Pending
1976-12-10
FR
FR7637266A
patent/FR2357528A1/en
active
Granted
1977
1977-04-01
US
US05/783,886
patent/US4098726A/en
not_active
Expired – Lifetime
1977-04-01
US
US05/783,885
patent/US4156693A/en
not_active
Expired – Lifetime
1978
1978-08-18
PH
PH21512A
patent/PH14726A/en
unknown
Also Published As
Publication number
Publication date
FR2357528A1
(en)
1978-02-03
DD131645A5
(en)
1978-07-12
US4016209A
(en)
1977-04-05
HU175963B
(en)
1980-11-28
IE44097B1
(en)
1981-08-12
AR223301A1
(en)
1981-08-14
PH14726A
(en)
1981-11-13
ATA290976A
(en)
1979-05-15
DE2617524A1
(en)
1976-11-04
FR2308375A1
(en)
1976-11-19
FR2308375B1
(en)
1981-07-31
DD131564A5
(en)
1978-07-05
PT65031A
(en)
1976-05-01
FI760939A
(en)
1976-10-24
GB1539006A
(en)
1979-01-24
IL49392A0
(en)
1976-06-30
CA1082228A
(en)
1980-07-22
AU506771B2
(en)
1980-01-24
US4098726A
(en)
1978-07-04
AT354099B
(en)
1979-12-27
JPS51136605A
(en)
1976-11-26
LU74759A1
(en)
1977-02-04
NL7603653A
(en)
1976-10-26
CS190529B2
(en)
1979-05-31
ZA762407B
(en)
1977-11-30
DK164576A
(en)
1976-10-24
AU1299176A
(en)
1977-10-20
NZ180581A
(en)
1978-11-13
PT65031B
(en)
1978-04-03
ES447059A1
(en)
1977-11-16
SE7604094L
(en)
1976-10-24
FR2357528B1
(en)
1980-09-26
US4156693A
(en)
1979-05-29
IL49392A
(en)
1980-07-31
GR59848B
(en)
1978-03-07
IE44097L
(en)
1976-10-23
NO761208L
(en)
1976-10-26
PL113974B1
(en)
1981-01-31
EG12656A
(en)
1979-06-30
BE841005A
(en)
1976-10-22
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Legal Events
Date
Code
Title
Description
1979-02-07
PS
Patent sealed [section 19, patents act 1949]
1982-11-10
PCNP
Patent ceased through non-payment of renewal fee