GB1586157A - Creación de Inventos y Patentes con Inteligencia Artificial

GB1586157A – Joint endoprosthesis
– Google Patents

GB1586157A – Joint endoprosthesis
– Google Patents
Joint endoprosthesis

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Publication number
GB1586157A

GB1586157A
GB25914/78A
GB2591478A
GB1586157A
GB 1586157 A
GB1586157 A
GB 1586157A
GB 25914/78 A
GB25914/78 A
GB 25914/78A
GB 2591478 A
GB2591478 A
GB 2591478A
GB 1586157 A
GB1586157 A
GB 1586157A
Authority
GB
United Kingdom
Prior art keywords
joint
endoprosthesis
metal
prosthesis
silicon
Prior art date
1977-07-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB25914/78A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Friatec AG

Original Assignee
Friedrichsfeld GmbH Steinzeug und Kunststoffwerke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1977-07-21
Filing date
1978-05-31
Publication date
1981-03-18

1978-05-31
Application filed by Friedrichsfeld GmbH Steinzeug und Kunststoffwerke
filed
Critical
Friedrichsfeld GmbH Steinzeug und Kunststoffwerke

1981-03-18
Publication of GB1586157A
publication
Critical
patent/GB1586157A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

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PNEYBMLMFCGWSK-UHFFFAOYSA-N
Alumina
Chemical compound

[O-2].[O-2].[O-2].[Al+3].[Al+3]
PNEYBMLMFCGWSK-UHFFFAOYSA-N
0.000
claims
description
15

IJGRMHOSHXDMSA-UHFFFAOYSA-N
Atomic nitrogen
Chemical compound

N#N
IJGRMHOSHXDMSA-UHFFFAOYSA-N
0.000
claims
description
8

239000000919
ceramic
Substances

0.000
claims
description
7

229960005363
aluminium oxide
Drugs

0.000
claims
description
5

238000005452
bending
Methods

0.000
claims
description
5

150000001875
compounds
Chemical class

0.000
claims
description
5

OKTJSMMVPCPJKN-UHFFFAOYSA-N
Carbon
Chemical compound

[C]
OKTJSMMVPCPJKN-UHFFFAOYSA-N
0.000
claims
description
4

238000004873
anchoring
Methods

0.000
claims
description
4

229910052799
carbon
Inorganic materials

0.000
claims
description
4

229910052757
nitrogen
Inorganic materials

0.000
claims
description
4

229910052710
silicon
Inorganic materials

0.000
claims
description
4

239000010703
silicon
Substances

0.000
claims
description
4

229910052581
Si3N4
Inorganic materials

0.000
claims
description
3

HBMJWWWQQXIZIP-UHFFFAOYSA-N
silicon carbide
Chemical compound

[Si+]#[C-]
HBMJWWWQQXIZIP-UHFFFAOYSA-N
0.000
claims
description
3

229910010271
silicon carbide
Inorganic materials

0.000
claims
description
3

HQVNEWCFYHHQES-UHFFFAOYSA-N
silicon nitride
Chemical compound

N12[Si]34N5[Si]62N3[Si]51N64
HQVNEWCFYHHQES-UHFFFAOYSA-N
0.000
claims
description
3

239000002184
metal
Substances

0.000
description
18

229910052751
metal
Inorganic materials

0.000
description
18

210000000988
bone and bone
Anatomy

0.000
description
7

239000004568
cement
Substances

0.000
description
7

229920003023
plastic
Polymers

0.000
description
6

239000004033
plastic
Substances

0.000
description
6

229920000573
polyethylene
Polymers

0.000
description
5

210000000689
upper leg
Anatomy

0.000
description
5

210000001624
hip
Anatomy

0.000
description
4

239000000463
material
Substances

0.000
description
4

150000002739
metals
Chemical class

0.000
description
4

239000002639
bone cement
Substances

0.000
description
3

230000007423
decrease
Effects

0.000
description
3

238000000034
method
Methods

0.000
description
3

229910018540
Si C
Inorganic materials

0.000
description
2

238000005299
abrasion
Methods

0.000
description
2

239000007943
implant
Substances

0.000
description
2

230000003137
locomotive effect
Effects

0.000
description
2

241001465754
Metazoa
Species

0.000
description
1

VVQNEPGJFQJSBK-UHFFFAOYSA-N
Methyl methacrylate
Chemical compound

COC(=O)C(C)=C
VVQNEPGJFQJSBK-UHFFFAOYSA-N
0.000
description
1

-1
Si 2 N 4
Chemical compound

0.000
description
1

229910000831
Steel
Inorganic materials

0.000
description
1

210000000588
acetabulum
Anatomy

0.000
description
1

229910045601
alloy
Inorganic materials

0.000
description
1

239000000956
alloy
Substances

0.000
description
1

238000010276
construction
Methods

0.000
description
1

230000003247
decreasing effect
Effects

0.000
description
1

229910001092
metal group alloy
Inorganic materials

0.000
description
1

239000002923
metal particle
Substances

0.000
description
1

238000007493
shaping process
Methods

0.000
description
1

230000003068
static effect
Effects

0.000
description
1

239000010959
steel
Substances

0.000
description
1

239000000126
substance
Substances

0.000
description
1

Classifications

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES

A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses

A61L27/28—Materials for coating prostheses

A61L27/30—Inorganic materials

A61L27/306—Other specific inorganic materials not covered by A61L27/303 – A61L27/32

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS

A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents

A61F2/02—Prostheses implantable into the body

A61F2/30—Joints

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61F2/02—Prostheses implantable into the body

A61F2/30—Joints

A61F2/32—Joints for the hip

C—CHEMISTRY; METALLURGY

C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON

C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients

C08K3/00—Use of inorganic substances as compounding ingredients

C08K3/10—Metal compounds

C08K3/14—Carbides

C—CHEMISTRY; METALLURGY

C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON

C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients

C08K3/00—Use of inorganic substances as compounding ingredients

C08K3/34—Silicon-containing compounds

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61F2/02—Prostheses implantable into the body

A61F2/30—Joints

A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth

A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61F2/02—Prostheses implantable into the body

A61F2/30—Joints

A61F2/3094—Designing or manufacturing processes

A61F2/30965—Reinforcing the prosthesis by embedding particles or fibres during moulding or dipping

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61F2/02—Prostheses implantable into the body

A61F2/30—Joints

A61F2/32—Joints for the hip

A61F2/36—Femoral heads ; Femoral endoprostheses

A61F2/3662—Femoral shafts

A61F2/367—Proximal or metaphyseal parts of shafts

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61F2/02—Prostheses implantable into the body

A61F2/30—Joints

A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth

A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves

A61F2002/3085—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with a threaded, e.g. self-tapping, bone-engaging surface, e.g. external surface

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61F2/02—Prostheses implantable into the body

A61F2/30—Joints

A61F2/32—Joints for the hip

A61F2/36—Femoral heads ; Femoral endoprostheses

A61F2/3609—Femoral heads or necks; Connections of endoprosthetic heads or necks to endoprosthetic femoral shafts

A61F2002/3625—Necks

A61F2002/3631—Necks with an integral complete or partial peripheral collar or bearing shoulder at its base

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61F2/02—Prostheses implantable into the body

A61F2/30—Joints

A61F2/32—Joints for the hip

A61F2/36—Femoral heads ; Femoral endoprostheses

A61F2/3662—Femoral shafts

A61F2002/3678—Geometrical features

A61F2002/369—Stepped shaft, i.e. having discrete diameter changes

Description

r ( 21) Application No 25914/78
In ( 31) Convention Application No.
2732922 » O ( 33) Fed Rep of Germany (DE) W W) ( 11) ( 22) Filed 31 May 1978 ( 32) Filed 21 July 1977 in ( 44) Complete Specification published 18 March 1981 ( 51) INT CL 3 A 61 F 1/03 ( 52) Index at acceptance A 5 R AJ ( 54) IMPROVEMENTS IN AND RELATING TO JOINT ENDOPROSTHESIS ( 71) We, FRIEDDICHSFELD GMBH STEINZEUG-UND KUNNSTSTOFFWERKE, a German Corporate Body of D 68 Mannheim 71, Postfach 7, Steinzeugstr 50, Germany, do hereby delcare the invention, for which we pray that a patent may be granted to us, and the method by which it is to be performed to be particularly described in and by the following statement:-
The invention relates to joint endoprosthesis, more particularly for the heavily stressed parts of the locomotor system, dense aluminium-oxide ceramic being provided along the articulating surfaces of the joint.
Joint endoprostheses are widely used to replace pathologically or traumatically damaged joints of the human locomotor system In earlier forms of these prostheses, the articulating surfaces consist either of metal or of a combination of metal and plastics In recent years the use of prostheses in which metal rubs on metal has been in continuous decline, since the coefficient of friction of such joints is relatively high and they suffer from considerable abrasion, the abraded metal particles being highly incompatible with the human organism The endoprostheses which are at present the most widely used for the heavily stressed joints are based on the use of some kinds of polythene and metal for the rubbing surfaces The polythene abrades more readily than the metal in this combination and the abraded polythene is much less harmful to the human organism than abraded metal Even so, sufficient polythene is abraded to make it necessary for the prostheses to be changed after at most from 10 to 15 years It has also been found that the polythene abrasion contributes to some forms of loosening of discrete components of such prostheses in the bone space contiguous with the joint.
One way of obviating wear of this kind of the articulating surfaces is for the two surfaces in rubbing contact to be made of a very dense very strong aluminium-oxide ceramic; a corresponding construction is disclosed e g in German Offenlegungsschrift No 2134316.
Even in these prostheses, however, all or some of the components used to anchor the prosthesis in the bone parts or spaces contiguous with the joint are made of metal 55 and the metal parts are either anchored in the bone space by means of a methylmethacrylate plastics bone cement or are introduced into the bone space without cement.
When cement is used, the total available 60 mechanical strength of the metal cannot be used since the elasticity moduli of the particular metals concerned permit such considerable deformations of the metal parts in response to heavy stresses that the 65 strength of the surrounding cement is exceeded and so the cement surround ruptures.
A rupture of this kind, which may well start just ‘as a very fine crack, in the surrounding of a metal prosthesis, e g in the 70 sac of plastics cement surrounding the intramedulldry stem of the thigh component of a total hip endoprosthesis, is bound to lead, if further alternate loading is experienced, to damage severe enough to 75 require replacement of the prosthesis When metal components of joint endoprostheses are anchored directly-i e, without the use of plastics bone cement-in the bone area near the joint, in a very high percent 80 age of cases loosening occurs after only a few years because of the limited biocompatibilty of the metals, so that, as in the previous case, the prosthesis finally has to be replaced In the latter case the parts 85 of the prosthesis can be of larger dimensions and therefore dimensionally more stable.
However, as stated above, the reasons for loosening of joints anchored directly without the use of cement lie rather more in the 90 limited compatibility of the particular metals used with the human organism than in deformation of the prosthesis Recently, efforts have been made to decrease the deformations experienced by metal parts as 95 a result of heavy stressing by enlarging e g.
the intramedullary stems of the thigh components of total hip endoprostheses Often, however, the resulting prostheses are almost too large to be implanted, while the sac of 100 PATENT SPECIFICATION
1 586 157 1 586 157 cement which still remains becomes so thin that there is a very considerable risk of rupturing.
This anchorage problem can be subdivided into two sub-problems, viz, in the case of cemented anchorages, some form of anchorage must be devised in which, for the same permanent strength as is possessed by the best of the metals previously used, there is less deformation than in the plastics bone cement surrounding the prostheses, and, in the case of non-cemented implants, biocompatibility is sufficient to ensure a dense growth of strong bone structures, suitable for receiving and transmitting loads, on the implant surface.
According to the invention there is provided a joint endoprosthesis comprising an articulating surface made of dense aluminium-oxide ceramic, and a part for anchoring the prosthesis made of a hotpressed compound of silicon with carbon and/or nitrogen having a bending strength of more than 600 N/mm 2.
Hot-pressed compounds of silicon with carbon andlor nitrogen are hard materials.
Their moduli of elasticity are more than 10 times greater than the moduli of elasticity of the metal alloys based on the noble steels or on cobalt-chromium-modybdenum alloys previously used for prostheses The bending strength of more than 600 N/mm 2 is the static bending strength of these Si compounds However, tests in conditions simulating conditions inside the body showed that the decrease in the strength of these materials as a function of alternating loads is very slight Even after 10 million alternating loads at bending stresses higher than occur continuously in prostheses, the strength was found to have decreased by only 25 %-i e, to about 450 N/mm 2 The Applicants’ own experiments on animals also show that this substance has a biocompatibility just as satisfactory as has been known for a long time for dense highpurity aluminium-oxide ceramic.
The strength tests referred to and the compatibility tests were made on hot pressed silicon nitride, Sis N, parts.
Joint prosthesis anchorage parts may therefore be made of this particular material.
Advantageously, however, joint endoprosthesis anchorage parts may be made of silicon carbide, Si C, which has similar advantages to Si 2 N 4.
Of course, the anchorage prosthesis parts according to the invention must in all cases be devised to suit the biomechanical condi 60 tions of the joint component concerned and, as far as possible, in a manner compatible with the material A shape or form in accordance with German patent application P 2627569 may be used for the femur 65 component of a hip endoprosthesis for anchorage using plastics bone cement, while forms or shapes such as disclosed by German patent specification 2 324 865, German
Auslegeschrift 2461 399 and German 70 Auslegeschrift 2517 702 may be used for the same component in an uncemented anchorage.
Various procedures are well known for the shaping of such prostheses and reference 75 should be made to German patent applications P 26 47 651 and P 26 56 761 for the most recent procedure.
The invention will be more fully understood from the following description of an 80 embodiment thereof, given by way of example only, with reference to the accompanying drawing of which the single Figure is a side view of an embodiment of a total hip endoprosthesis The endoprosthesis 85 comprises a socket or artificial acetabulum 1 made of a dense high-strength A 1202 ceramic and has a substantially hemispherical recess 2 having a very highly polished surface When fitted in the re 90 cipient and ready for use, the recess 2 receives an end member or artificial femoral head 3 of a femur component of the prosthesis Member 3 is made of dense high-strength A 1202 ceramic, is substantially 95 part-spherical and has a very highly polished spherical surface The two highly polished surfaces are the articulating surfaces of the joint The replacement femoral head 3 is anchored in the medullary space 100 of the femur by means of an intramedullary stem 4 which, as shown, is in the shape of a stepped stem for an uncemented anchorage As shown, the connection between the member 3 and the stem 4 can be 105 made by way of a self-locking cone 5 The stem 4 is made of a hot-pressed compound of silicon with carbon andlor nitrogen, e g.
of silicon nitride, Si 2 N 4, or silicon carbide, Si C 110 1 586 157

Claims (4)

WHAT WE CLAIM IS:-

1 A joint endoprosthesis comprising an articulating surface made of dense aluminium-oxide ceramic, and a part for anchoring the prosthesis made of a hotpressed compound of silicon with carbon and/or nitrogen having a bending strength of more than 600 N/mm 2.

2 An endoprosthesis according to claim 1 wherein the anchoring part is made of silicon nitride, Si 2 N 4.

3 An endoprosthesis acording to claim 1, wherein the anchoring part is made of silicon carbide, Si C.

4 A joint endoprosthesis according to 15 claim 1 substantially as herein described.
A joint endopro Sthesis substantially as herein described with reference to the accompanying drawing.
A A THORNTON & CO, Northumberland House, 303-306 High Holborn, London, W C 1.
Printed for Her Majesty’s Stationery Office by The Tweeddale Press Ltd, Berwick-upon-Tweed, 1981.
Published at the Patent Office, 25 Southampton Buildings, London, WC 2 A l AY, from which copies may be obtained.

GB25914/78A
1977-07-21
1978-05-31
Joint endoprosthesis

Expired

GB1586157A
(en)

Applications Claiming Priority (1)

Application Number
Priority Date
Filing Date
Title

DE19772732923

DE2732923A1
(en)

1977-07-21
1977-07-21

JOINT PROSTHESIS MADE OF NON-METALLIC MATERIALS

Publications (1)

Publication Number
Publication Date

GB1586157A
true

GB1586157A
(en)

1981-03-18

Family
ID=6014487
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB25914/78A
Expired

GB1586157A
(en)

1977-07-21
1978-05-31
Joint endoprosthesis

Country Status (8)

Country
Link

US
(1)

US4184213A
(en)

JP
(1)

JPS5463586A
(en)

BE
(1)

BE868283A
(en)

DE
(1)

DE2732923A1
(en)

FR
(1)

FR2400354A1
(en)

GB
(1)

GB1586157A
(en)

IT
(1)

IT1097178B
(en)

NL
(1)

NL7805552A
(en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU524452B2
(en)

1978-07-17
1982-09-16
Unisearch Limited
Surgical endoprotheses

US4327014A
(en)

1979-04-11
1982-04-27
Kanebo Ltd.
Resin-forming material, implant material and compositions for restorative material suitable for medical or dental use

DE3233992C2
(en)

1982-09-14
1984-08-30
Friedrichsfeld Gmbh, Steinzeug- Und Kunststoffwerke, 6800 Mannheim

Ceramic implants

CH656525A5
(en)

1982-10-15
1986-07-15
Sulzer Ag

ANCHOR STEM FOR ANCHORING A JOINT REPLACEMENT.

US5007932A
(en)

1985-01-08
1991-04-16
Ngk Spark Plug Co., Ltd.
Artificial bone joint

US4840630A
(en)

1986-06-05
1989-06-20
Kyocera Corporation
Artificial hip joint

FR2633179B1
(en)

1988-06-28
1992-03-27
Desmarquest Ceramiques Tech

IMPROVED ASSEMBLY OF A CERAMIC HEAD ON A METAL ROD FOR HIP PROSTHESIS

US5002580A
(en)

1988-10-07
1991-03-26
Pfizer Hospital Products Group, Inc.
Prosthetic device and method of implantation

US5147408A
(en)

1988-10-07
1992-09-15
Pfizer Hospital Products Group, Inc.
Prosthetic device and method of implantation

US5062854A
(en)

1988-10-07
1991-11-05
Pfizer Hospital Products Group
Prosthetic device and method of implantation

US4966108A
(en)

1989-04-28
1990-10-30
Cummins Engine Company, Inc.
Sintered ceramic ball and socket joint assembly

US7396594B2
(en)

2002-06-24
2008-07-08
The Trustees Of Princeton University
Carrier applied coating layers

US7597715B2
(en)

2005-04-21
2009-10-06
Biomet Manufacturing Corp.
Method and apparatus for use of porous implants

US8123814B2
(en)

2001-02-23
2012-02-28
Biomet Manufacturing Corp.
Method and appartus for acetabular reconstruction

US6682567B1
(en)

2001-09-19
2004-01-27
Biomet, Inc.
Method and apparatus for providing a shell component incorporating a porous ingrowth material and liner

AUPS105202A0
(en)

†

2002-03-12
2002-04-11
Tna Australia Pty Limited
A conveyor

US8266780B2
(en)

2005-04-21
2012-09-18
Biomet Manufacturing Corp.
Method and apparatus for use of porous implants

US8021432B2
(en)

2005-12-05
2011-09-20
Biomet Manufacturing Corp.
Apparatus for use of porous implants

US8292967B2
(en)

2005-04-21
2012-10-23
Biomet Manufacturing Corp.
Method and apparatus for use of porous implants

US8066778B2
(en)

2005-04-21
2011-11-29
Biomet Manufacturing Corp.
Porous metal cup with cobalt bearing surface

US7635447B2
(en)

2006-02-17
2009-12-22
Biomet Manufacturing Corp.
Method and apparatus for forming porous metal implants

EP2205188B1
(en)

2007-09-25
2014-04-09
Biomet Manufacturing Corp.
Cementless tibial tray

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Publication date
Assignee
Title

US3647517A
(en)

1970-06-22
1972-03-07
Chromalloy American Corp
Impact resistant coatings for cobalt-base superalloys and the like

FR2096895B1
(en)

1970-07-10
1973-01-12
Electro Ceramique Cie Gl

US3924275A
(en)

1973-05-17
1975-12-09
Friedrichsfeld Gmbh
Artifical joint prosthesis using Al{hd 2{b O{HD 3{B {0 material

US4012795A
(en)

1974-10-29
1977-03-22
Feldmuhle Anlagen- Und Produktionsgesellschaft Mit Beschrankter Haftung
Artificial head assembly for an articulated joint between two bones

DE2451275C2
(en)

1974-10-29
1982-08-26
Feldmühle AG, 4000 Düsseldorf

Head part of a hip joint prosthesis to be implanted

DE2461339B2
(en)

1974-12-24
1976-10-07
Friedrichsfeld Gmbh, Steinzeug- Und Kunststoffwerke, 6800 Mannheim

THIGH PART OF A TOTAL HIP JOINT PROSTHESIS FOR CEMENT-FREE IMPLANTATION

CH602095A5
(en)

1974-12-24
1978-07-31
Friedrichsfeld Gmbh

FR2301217A2
(en)

1975-02-21
1976-09-17
Ceraver
Hip prosthesis in alumina – with acetabular part having ridge and grooved anchoring heads

1977

1977-07-21
DE
DE19772732923
patent/DE2732923A1/en
active
Pending

1978

1978-05-23
NL
NL7805552A
patent/NL7805552A/en
not_active
Application Discontinuation

1978-05-31
GB
GB25914/78A
patent/GB1586157A/en
not_active
Expired

1978-06-15
US
US05/915,779
patent/US4184213A/en
not_active
Expired – Lifetime

1978-06-20
BE
BE188703A
patent/BE868283A/en
unknown

1978-07-17
IT
IT7825778A
patent/IT1097178B/en
active

1978-07-19
JP
JP8722878A
patent/JPS5463586A/en
active
Pending

1978-07-20
FR
FR7821571A
patent/FR2400354A1/en
not_active
Withdrawn

Also Published As

Publication number
Publication date

IT1097178B
(en)

1985-08-26

US4184213A
(en)

1980-01-22

NL7805552A
(en)

1979-01-23

IT7825778D0
(en)

1978-07-17

BE868283A
(en)

1978-10-16

JPS5463586A
(en)

1979-05-22

FR2400354A1
(en)

1979-03-16

DE2732923A1
(en)

1979-01-25

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