GB2001995A – An immunostimulant, a process for preparing it, and compositions containing it
– Google Patents
GB2001995A – An immunostimulant, a process for preparing it, and compositions containing it
– Google Patents
An immunostimulant, a process for preparing it, and compositions containing it
Info
Publication number
GB2001995A
GB2001995A
GB7831772A
GB7831772A
GB2001995A
GB 2001995 A
GB2001995 A
GB 2001995A
GB 7831772 A
GB7831772 A
GB 7831772A
GB 7831772 A
GB7831772 A
GB 7831772A
GB 2001995 A
GB2001995 A
GB 2001995A
Authority
GB
United Kingdom
Prior art keywords
immunostimulant
water
substance
soluble
alpha
Prior art date
1977-08-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB7831772A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bpifrance Financement SA
Original Assignee
Agence National de Valorisation de la Recherche ANVAR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1977-08-04
Filing date
1978-07-31
Publication date
1979-02-14
1978-07-31
Application filed by Agence National de Valorisation de la Recherche ANVAR
filed
Critical
Agence National de Valorisation de la Recherche ANVAR
1979-02-14
Publication of GB2001995A
publication
Critical
patent/GB2001995A/en
Status
Withdrawn
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
C12P21/00—Preparation of peptides or proteins
C12P21/005—Glycopeptides, glycoproteins
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
A61K35/66—Microorganisms or materials therefrom
A61K35/74—Bacteria
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
A61P31/12—Antivirals
C—CHEMISTRY; METALLURGY
C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
C12N1/20—Bacteria; Culture media therefor
C12N1/205—Bacterial isolates
C—CHEMISTRY; METALLURGY
C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 – C12P39/00, by using microorganisms or enzymes
C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 – C12P39/00, by using microorganisms or enzymes by using actinomycetales
C—CHEMISTRY; METALLURGY
C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C – C12Q, RELATING TO MICROORGANISMS
C12R2001/00—Microorganisms ; Processes using microorganisms
C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
C12R2001/465—Streptomyces
Abstract
An immunostimulant substance, denoted 34129 RP, is obtained from delipidated cells of Streptomyces stimulosus DS 25556 (NRRL 5776), by a process which comprises subjecting these delipidated cells to repeated autolysis, thereafter fractionating the water-soluble portion of the autolysis product by ultrafiltration to obtain substances whose molecular weight is 2000 to 20,000, and isolating the water- soluble substance 34129RP thus obtained after lyophilization of the solution. The immunostimulant substance is water-soluble, and can be administered by numerous routes to humans and to animals, preferably in the form of conventional pharmaceutical formulations. The immunostimulant, which has an elementary analysis; C40.4-41.1%; H 6.7-6.9%, N 8.0-10.6%, comprises alamine (5 to 7%), glutamic acid (7 to 10%), glycine (2.5 to 4%), alpha , alpha , diaminopimelic acid (5 to 8%), N-acetyl- glucosamine (5 to 10%) and muramic acid (5 to 10%).
GB7831772A
1977-08-04
1978-07-31
An immunostimulant, a process for preparing it, and compositions containing it
Withdrawn
GB2001995A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
FR7724092A
FR2399437A1
(en)
1977-08-04
1977-08-04
NEW IMMUNOSTIMULANT SUBSTANCE, ITS PREPARATION PROCESS AND THE COMPOSITIONS CONTAINING IT
Publications (1)
Publication Number
Publication Date
GB2001995A
true
GB2001995A
(en)
1979-02-14
Family
ID=9194245
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB7831772A
Withdrawn
GB2001995A
(en)
1977-08-04
1978-07-31
An immunostimulant, a process for preparing it, and compositions containing it
Country Status (6)
Country
Link
JP
(1)
JPS5427502A
(en)
BE
(1)
BE869058A
(en)
DE
(1)
DE2833799A1
(en)
FR
(1)
FR2399437A1
(en)
GB
(1)
GB2001995A
(en)
NL
(1)
NL7807938A
(en)
Families Citing this family (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
FR2466455A2
(en)
*
1979-10-05
1981-04-10
Anvar
Immunostimulant and adjuvant N-acyl-peptide derivs. – produced by N-acylation of peptides from streptomyces stimulosus water-soluble extract (BE 17.4.80)
GB2033906B
(en)
*
1978-10-19
1982-12-01
Anvar
Water-soluble compounds derived from extracts of streptomyces stimulosus process for their production and compositions containing them
JPS5766836U
(en)
*
1980-10-07
1982-04-21
1977
1977-08-04
FR
FR7724092A
patent/FR2399437A1/en
not_active
Withdrawn
1978
1978-07-17
BE
BE189329A
patent/BE869058A/en
unknown
1978-07-26
NL
NL787807938A
patent/NL7807938A/en
not_active
Application Discontinuation
1978-07-31
GB
GB7831772A
patent/GB2001995A/en
not_active
Withdrawn
1978-08-02
DE
DE19782833799
patent/DE2833799A1/en
active
Pending
1978-08-04
JP
JP9468578A
patent/JPS5427502A/en
active
Pending
Also Published As
Publication number
Publication date
JPS5427502A
(en)
1979-03-01
FR2399437A1
(en)
1979-03-02
BE869058A
(en)
1979-01-17
DE2833799A1
(en)
1979-02-15
NL7807938A
(en)
1979-02-06
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Legal Events
Date
Code
Title
Description
1980-02-13
WAP
Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)
