GB2016499A – Inclusion complexes of indomethacin their preparation and pharmaceutical compositions containing them
– Google Patents
GB2016499A – Inclusion complexes of indomethacin their preparation and pharmaceutical compositions containing them
– Google Patents
Inclusion complexes of indomethacin their preparation and pharmaceutical compositions containing them
Info
Publication number
GB2016499A
GB2016499A
GB7902710A
GB7902710A
GB2016499A
GB 2016499 A
GB2016499 A
GB 2016499A
GB 7902710 A
GB7902710 A
GB 7902710A
GB 7902710 A
GB7902710 A
GB 7902710A
GB 2016499 A
GB2016499 A
GB 2016499A
Authority
GB
United Kingdom
Prior art keywords
indomethacin
preparation
pharmaceutical compositions
compositions containing
inclusion complexes
Prior art date
1978-01-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7902710A
Other versions
GB2016499B
(en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1978-01-27
Filing date
1979-01-25
Publication date
1979-09-26
1979-01-25
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
filed
Critical
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
1979-09-26
Publication of GB2016499A
publication
Critical
patent/GB2016499A/en
1982-07-28
Application granted
granted
Critical
1982-07-28
Publication of GB2016499B
publication
Critical
patent/GB2016499B/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
B—PERFORMING OPERATIONS; TRANSPORTING
B82—NANOTECHNOLOGY
B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/33—Heterocyclic compounds
A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
A61K31/404—Indoles, e.g. pindolol
A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
C07D209/04—Indoles; Hydrogenated indoles
C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
C—CHEMISTRY; METALLURGY
C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 – C08B35/00; Derivatives thereof
C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
GB7902710A
1978-01-27
1979-01-25
Inclusion complexes of indomethacin their preparation and pharmaceutical compositions containing them
Expired
GB2016499B
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
HU78CI1803A
HU176215B
(en)
1978-01-27
1978-01-27
Process for preparing a cyclodextrin-indomethacin inclusion complex with a ratio of at about 2:1
Publications (2)
Publication Number
Publication Date
GB2016499A
true
GB2016499A
(en)
1979-09-26
GB2016499B
GB2016499B
(en)
1982-07-28
Family
ID=10994689
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB7902710A
Expired
GB2016499B
(en)
1978-01-27
1979-01-25
Inclusion complexes of indomethacin their preparation and pharmaceutical compositions containing them
Country Status (23)
Country
Link
US
(1)
US4228160A
(en)
JP
(1)
JPS54117018A
(en)
AT
(1)
AT360554B
(en)
AU
(1)
AU518750B2
(en)
BE
(1)
BE873725A
(en)
CA
(1)
CA1119115A
(en)
CH
(1)
CH638819A5
(en)
CS
(1)
CS207742B2
(en)
DD
(1)
DD141312A1
(en)
DE
(1)
DE2902297A1
(en)
DK
(1)
DK154977C
(en)
ES
(1)
ES477181A1
(en)
FI
(1)
FI65441C
(en)
FR
(1)
FR2415631A1
(en)
GB
(1)
GB2016499B
(en)
HU
(1)
HU176215B
(en)
IL
(1)
IL56309A
(en)
IT
(1)
IT1118282B
(en)
NL
(1)
NL7808792A
(en)
NO
(1)
NO146637C
(en)
PL
(1)
PL117208B1
(en)
SE
(1)
SE445353B
(en)
SU
(1)
SU915807A3
(en)
Cited By (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
GB2124489A
(en)
*
1982-07-19
1984-02-22
Ciba Geigy Ag
Medicinal composition containing pirprofen and cyclodextrin
US5079237A
(en)
*
1988-01-18
1992-01-07
Lek
Inclusion complex of nicardipine or its hydrochloride with beta-cyclodextrin and a sustained release pharmaceutical preparation containing the same
Families Citing this family (56)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US2606074A
(en)
*
1946-08-21
1952-08-05
Edward H Ackermann
Air distributing nozzle
US4352793A
(en)
*
1979-04-26
1982-10-05
Sumitomo Chemical Company, Limited
Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin
DE2947742C2
(en)
*
1979-11-27
1986-04-03
Koch, Jürgen, Dr., 2000 Hamburg
Medicaments containing β-cyclodextrin
HU184066B
(en)
*
1979-12-28
1984-06-28
Chinoin Gyogyszer Es Vegyeszet
Plant growth regulating substance and process for preparing such compound
HU181733B
(en)
*
1980-08-07
1983-11-28
Chinoin Gyogyszer Es Vegyeszet
Process for preparing sorbents containing cyclodextrin on cellulose base
HU182217B
(en)
*
1980-10-17
1983-12-28
Chinoin Gyogyszer Es Vegyeszet
Process for producing inclusive complexes of cyclodextrines and strong inorganic oxyacids
JPS5830032B2
(en)
*
1981-02-18
1983-06-27
呉羽化学工業株式会社
Bifidus bacteria growth agent
HU183430B
(en)
*
1981-05-12
1984-05-28
Chinoin Gyogyszer Es Vegyeszet
Process for producing cyclodextrine inclusion complexes of n-bracket-1-phenylethyl-bracket closed-3,3-diphenylpropylamine or n-bracket-1-phenylethyl-bracket closed-3,3-diphenylpropylamine-hydrochloride
JPS58177949A
(en)
*
1982-04-12
1983-10-18
Takeda Chem Ind Ltd
Clathrate compound of lankacidin-group antibiotic substance
US4425336A
(en)
1982-05-24
1984-01-10
Key Pharmaceuticals, Inc.
3,4-Dihydroxy-N-[3-(4-dihydroxyphenyl)-1-methyl-n-propyl]-beta-phenethylamine cyclodextrin complexes
HU190818B
(en)
*
1982-11-09
1986-11-28
Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu
Process for producing complexes of piperonyl-butoxide-cyclodextrin
HU191101B
(en)
*
1983-02-14
1987-01-28
Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu
Process for preparing water-soluble cyclodextrin polymers substituted with ionic groups
US4502930A
(en)
*
1983-06-27
1985-03-05
Agency Of Industrial Science & Technology
Method for manufacture of 7-substituted quadricyclene-cyclodextrin inclusion compound
JPS6025967A
(en)
*
1983-07-21
1985-02-08
Eisai Co Ltd
Tripamide clathrate compound
US4675395A
(en)
*
1984-03-14
1987-06-23
Seiwa Technological Laboratories Limited
Cyclodextrin inclusion compound and process for its preparation
JPS60202115A
(en)
*
1984-03-27
1985-10-12
Ichiro Shibauchi
Curing agent for epoxy resin, and curing of said epoxy resin
DE3427787A1
(en)
*
1984-07-27
1986-01-30
Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz
ACTIVE SUBSTANCE COMPLEXES OF 5-METHOXY-2 ((4-METHOXY-3,5-DIMETHYL-2-PYRIDYL) METHYLSULFINYL) -1H-BENZIMIDAZOLE WITH CYCLODEXTRINES, THEIR PRODUCTION AND MEDICINAL PRODUCTS
YU43290B
(en)
*
1986-11-13
1989-06-30
Lek Tovarna Farmacevtskih
Process for preparing inclusioned complex of ibuproxane with beta-cyclodextrine
IT1204725B
(en)
*
1987-06-17
1989-03-10
Edmond Pharma Srl
DIPYRIDAMOL INCLUSION COMPLEXES WITH CYCLODESTRINE
US4885275A
(en)
*
1987-10-15
1989-12-05
Eli Lilly And Company
Vancomycin-HCL solutions and the lyophilization thereof
US5017566A
(en)
*
1987-12-30
1991-05-21
University Of Florida
Redox systems for brain-targeted drug delivery
US5002935A
(en)
*
1987-12-30
1991-03-26
University Of Florida
Improvements in redox systems for brain-targeted drug delivery
DE3809808A1
(en)
*
1988-03-23
1989-10-05
Hexal Pharma Gmbh & Co Kg
SOLIDS, ESPECIALLY FESTORAL AND RECTAL, ETOFENAMATE-CONTAINING MEDICINAL PRODUCTS
US5997856A
(en)
*
1988-10-05
1999-12-07
Chiron Corporation
Method and compositions for solubilization and stabilization of polypeptides, especially proteins
CA2013485C
(en)
*
1990-03-06
1997-04-22
John Michael Gardlik
Solid consumer product compositions containing small particle cyclodextrin complexes
US5139687A
(en)
*
1990-05-09
1992-08-18
The Proctor & Gamble Company
Non-destructive carriers for cyclodextrin complexes
US5384186A
(en)
*
1990-05-09
1995-01-24
The Proctor & Gamble Company
Non-destructive carriers for cyclodextrin complexes
US5246611A
(en)
*
1990-05-09
1993-09-21
The Procter & Gamble Company
Non-destructive carriers for cyclodextrin complexes
JPH07583B2
(en)
*
1990-11-21
1995-01-11
北海道糖業株式会社
Water-soluble pentacyclic triterpene clathrate compound, method for producing the same, and food, beverage and oral composition using the same
US5321014A
(en)
*
1991-06-28
1994-06-14
The United States Of America As Represented By The Department Of Health And Human Services
Molecular encapsulation and delivery of alkenes alkynes and long chain alkanes, to living mammalian cells
US20040014695A1
(en)
*
1992-06-19
2004-01-22
Supergen, Inc.
Pharmaceutical formulation
US5602112A
(en)
1992-06-19
1997-02-11
Supergen, Inc.
Pharmaceutical formulation
US5403828A
(en)
*
1992-08-13
1995-04-04
American Maize-Products Company
Purification of cyclodextrin complexes
JPH10500982A
(en)
*
1994-05-27
1998-01-27
ファーマーク、ネダーランド、ベスローテン、フェンノートシャップ
Pharmaceutical composition
ZA959469B
(en)
*
1994-11-15
1996-05-15
South African Druggists Ltd
Pharmaceutical composition
US5744154A
(en)
*
1995-09-06
1998-04-28
Laboratoire Chauvin S.A.
Ready-to-use indomethacin-based eye lotion
US5824668A
(en)
*
1996-11-07
1998-10-20
Supergen, Inc.
Formulation for administration of steroid compounds
US5942501A
(en)
*
1996-08-16
1999-08-24
Collaborative Laboratories, Inc.
Cyclodextrin derivative complex
US6287603B1
(en)
*
1999-09-16
2001-09-11
Nestec S.A.
Cyclodextrin flavor delivery systems
US20020176842A1
(en)
*
2001-04-09
2002-11-28
Lyn Hughes
Extended release of active ingredients
KR100473716B1
(en)
*
2002-03-27
2005-03-08
주식회사 참 존
Inclusion complex of 7-dehydrocholesterol and cyclodextrin, cosmetic compositions containing the same and method of stabilizing 7-dehydrocholeserol
WO2006137959A1
(en)
*
2005-06-13
2006-12-28
Cargill, Incorporated
Cyclodextrin inclusion complexes and methods of preparing same
CA2610471A1
(en)
*
2005-06-13
2006-12-28
Cargill, Incorporated
Cyclodextrin inclusion complexes and methods of preparing same
US20070009532A1
(en)
*
2005-07-06
2007-01-11
Branimir Sikic
Treatment of patients with cancer using a calicheamicin-antibody conjugate in combination with zosuquidar
US20070010485A1
(en)
*
2005-07-06
2007-01-11
Jeff Schwegman
Chemotherapeutic formulations of zosuquidar trihydrochloride and modified cyclodextrins
US20070010487A1
(en)
*
2005-07-06
2007-01-11
Jeff Schwegman
Chemotherapeutic formulations of zosuquidar trihydrochloride and modified cyclodextrins
US20070010486A1
(en)
*
2005-07-06
2007-01-11
Jeff Schwegman
Chemotherapeutic formulations of zosuquidar trihydrochloride and modified cyclodextrins
US20070010466A1
(en)
*
2005-07-06
2007-01-11
Branimir Sikic
Zosuquidar, daunorubicin, and cytarabine for the treatment of cancer
US20090185985A1
(en)
*
2006-06-13
2009-07-23
Cargill, Incorporated
Large-particle cyclodextrin inclusion complexes and methods of preparing same
JP2010514794A
(en)
*
2006-12-27
2010-05-06
カーギル インコーポレイテッド
Cyclodextrin-encapsulated complex and method for preparing the complex
US20080283693A1
(en)
*
2007-05-15
2008-11-20
Evans Michael J F
Propulsion apparatus and system
US20110300127A1
(en)
*
2008-05-27
2011-12-08
Fujifilm Corporation
Drug-containing composition
FR2989001B1
(en)
*
2012-04-06
2017-07-21
Centre Nat Rech Scient
MICROPARTICLES AND NANOPARTICLES COMPRISING HYDROPHOBIC POLYSACCHARIDES AND ALPHA-CYCLODEXTRIN
RS62097B1
(en)
2016-02-04
2021-08-31
Czap Research And Development Llc
Controlled-release and stratified cyclodextrin inclusion complex vehicles
CN107184989B
(en)
*
2017-05-18
2020-09-08
宁夏蓝博思化学技术有限公司
Liquiritigenin-cyclodextrin or cyclodextrin derivative inclusion compound, composition, preparation method and application
CN107158403B
(en)
*
2017-05-18
2020-09-08
宁夏蓝博思化学技术有限公司
Isoliquiritigenin-cyclodextrin or cyclodextrin derivative inclusion compound, composition, preparation method and application
Family Cites Families (4)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US2959580A
(en)
*
1956-10-17
1960-11-08
Univ Minnesota
Formation of inclusion compounds
US3061444A
(en)
*
1960-10-07
1962-10-30
Gen Foods Corp
Inclusion compounds incorporating edible juice constituents
DE1620030B1
(en)
1961-03-22
1970-03-05
Merck & Co Inc
Process for the preparation of indolyl- (3) -alkanecarboxylic acids and their salts
US4054736A
(en)
*
1970-06-10
1977-10-18
Ono Pharmaceutical Co., Ltd.
Clathrate compounds of prostaglandins or their analogues with cyclodextrin
1978
1978-01-27
HU
HU78CI1803A
patent/HU176215B/en
not_active
IP Right Cessation
1978-08-25
NL
NL7808792A
patent/NL7808792A/en
not_active
Application Discontinuation
1978-12-26
IL
IL56309A
patent/IL56309A/en
not_active
IP Right Cessation
1979
1979-01-11
IT
IT67050/79A
patent/IT1118282B/en
active
1979-01-18
SE
SE7900479A
patent/SE445353B/en
not_active
IP Right Cessation
1979-01-19
CS
CS79445A
patent/CS207742B2/en
unknown
1979-01-22
DE
DE19792902297
patent/DE2902297A1/en
active
Granted
1979-01-22
FI
FI790198A
patent/FI65441C/en
not_active
IP Right Cessation
1979-01-24
FR
FR7901796A
patent/FR2415631A1/en
active
Granted
1979-01-24
US
US06/006,185
patent/US4228160A/en
not_active
Expired – Lifetime
1979-01-25
AU
AU43671/79A
patent/AU518750B2/en
not_active
Ceased
1979-01-25
DD
DD79210634A
patent/DD141312A1/en
unknown
1979-01-25
GB
GB7902710A
patent/GB2016499B/en
not_active
Expired
1979-01-25
JP
JP765679A
patent/JPS54117018A/en
active
Pending
1979-01-26
ES
ES477181A
patent/ES477181A1/en
not_active
Expired
1979-01-26
DK
DK035079A
patent/DK154977C/en
active
1979-01-26
NO
NO790261A
patent/NO146637C/en
unknown
1979-01-26
PL
PL1979213015A
patent/PL117208B1/en
unknown
1979-01-26
CA
CA000320353A
patent/CA1119115A/en
not_active
Expired
1979-01-26
AT
AT59179A
patent/AT360554B/en
not_active
IP Right Cessation
1979-01-26
CH
CH81779A
patent/CH638819A5/en
not_active
IP Right Cessation
1979-01-26
SU
SU792718201A
patent/SU915807A3/en
active
1979-01-26
BE
BE193088A
patent/BE873725A/en
not_active
IP Right Cessation
Cited By (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
GB2124489A
(en)
*
1982-07-19
1984-02-22
Ciba Geigy Ag
Medicinal composition containing pirprofen and cyclodextrin
US5079237A
(en)
*
1988-01-18
1992-01-07
Lek
Inclusion complex of nicardipine or its hydrochloride with beta-cyclodextrin and a sustained release pharmaceutical preparation containing the same
Also Published As
Publication number
Publication date
DK154977C
(en)
1989-06-12
IL56309A
(en)
1981-09-13
AU4367179A
(en)
1979-08-02
BE873725A
(en)
1979-05-16
NO790261L
(en)
1979-07-30
FI65441C
(en)
1984-05-10
CA1119115A
(en)
1982-03-02
CS207742B2
(en)
1981-08-31
GB2016499B
(en)
1982-07-28
NL7808792A
(en)
1979-07-31
JPS54117018A
(en)
1979-09-11
IT7967050D0
(en)
1979-01-11
IT1118282B
(en)
1986-02-24
ES477181A1
(en)
1979-10-16
PL117208B1
(en)
1981-07-31
FR2415631A1
(en)
1979-08-24
NO146637C
(en)
1982-11-10
CH638819A5
(en)
1983-10-14
FR2415631B1
(en)
1981-12-24
DE2902297C2
(en)
1989-02-09
NO146637B
(en)
1982-08-02
SU915807A3
(en)
1982-03-23
US4228160A
(en)
1980-10-14
AU518750B2
(en)
1981-10-15
DE2902297A1
(en)
1979-08-02
FI65441B
(en)
1984-01-31
DK154977B
(en)
1989-01-16
DD141312A1
(en)
1980-04-23
FI790198A
(en)
1979-07-28
DK35079A
(en)
1979-07-28
HU176215B
(en)
1981-01-28
SE445353B
(en)
1986-06-16
PL213015A1
(en)
1979-12-17
ATA59179A
(en)
1980-06-15
SE7900479L
(en)
1979-07-28
AT360554B
(en)
1981-01-26
Similar Documents
Publication
Publication Date
Title
GB2016499B
(en)
1982-07-28
Inclusion complexes of indomethacin their preparation and pharmaceutical compositions containing them
IL56992A0
(en)
1979-07-25
N-heterocyclyl-4-piperidinamines their preparation and pharmaceutical compositions containing them
IL56411A
(en)
1982-09-30
Derivatives of 4-amino-5-alkylsulphonyl-ortho-anisamides,their preparation and pharmaceutical compositions containing them
IL58079A0
(en)
1979-12-30
Fabrinolytic enzyme derivatives their preparation and pharmaceutical compositions containing them
IL59004A0
(en)
1980-03-31
Substituted benzamides their preparation and pharmaceutical compositions containing them
IL58579A0
(en)
1980-01-31
Nitrogen heterocyclic compounds their preparation and pharmaceutical compositions containing them
IL56407A
(en)
1983-05-15
4-amino-3-sulfamoylpyridyl derivatives and pharmaceutical compositions containing them
IL57849A
(en)
1985-10-31
Imidazole derivatives and pharmaceutical compositions containing same
GB2061987B
(en)
1983-05-18
Cyclodextrin complexes their preparation and pharmaceutical compositions containing them
IL58730A0
(en)
1980-02-29
Spiro-polycyclic imidazolidinedione derivatives and pharmaceutical compositions containing them
IL57040A0
(en)
1979-07-25
Mercaptoimidazole derivatives their preparation and pharmaceutical compositions containing them
IL56821A0
(en)
1979-05-31
Heterocycylcarbonyl derivatives of ure and pharmaceutical composition containing them
IL56678A0
(en)
1979-05-31
Substituted2-phenyl imino-inidazolidines and salts thereoftheir preparation and pharmaceutical compositions containing them
IL57268A0
(en)
1979-09-30
Di-o-n-alkyl clycerol derivatives and pharmaceutical compositions containing them
IL58415A0
(en)
1980-01-31
Phenyl-quinolizidines their manufacture and pharmaceutical compositions containing them
PH18056A
(en)
1985-03-18
Pharmaceutical formulations of cisplatin
GB2044756B
(en)
1982-12-22
Fluoro-amines processes for their preparation and pharmaceutical compositions containing them
IL58681A0
(en)
1980-02-29
Heterocyclic compounds their preparation and pharmaceutical compositions containing them
IL57476A0
(en)
1979-10-31
Compounds of the muramy-peptide type and pharmaceutical compositions containing them
IL58620A0
(en)
1980-02-29
Aryltrifluoroethanol derivatives their preparation and pharmaceutical compositions containing them
NZ189899A
(en)
1982-05-25
Dilignols and dilignol-type compounds pharmaceutical compositions
NZ190245A
(en)
1981-03-16
Isoquinoline derivatives and pharmaceutical compositions containing them
IL58391A0
(en)
1980-01-31
Cyclohexadiene derivatives their preparation and pharmaceutical compositions containing them
IL58438A0
(en)
1980-01-31
Isoquinoline derivatives their preparation and pharmaceutical compositions containing them
IL58229A0
(en)
1979-12-30
Aurone derivatives their preparation and pharmaceutical compositions containing them
Legal Events
Date
Code
Title
Description
1985-07-24
746
Register noted ‘licences of right’ (sect. 46/1977)
1994-09-21
PCNP
Patent ceased through non-payment of renewal fee
Effective date:
19940125
