GB2018756B

GB2018756B – 2-(2-thenoylthio)-propionylglycine: method for its preparation and pharmaceutical formulations containing said compound
– Google Patents

GB2018756B – 2-(2-thenoylthio)-propionylglycine: method for its preparation and pharmaceutical formulations containing said compound
– Google Patents
2-(2-thenoylthio)-propionylglycine: method for its preparation and pharmaceutical formulations containing said compound

Info

Publication number
GB2018756B

GB2018756B
GB7912768A
GB7912768A
GB2018756B
GB 2018756 B
GB2018756 B
GB 2018756B
GB 7912768 A
GB7912768 A
GB 7912768A
GB 7912768 A
GB7912768 A
GB 7912768A
GB 2018756 B
GB2018756 B
GB 2018756B
Authority
GB
United Kingdom
Prior art keywords
thenoylthio
propionylglycine
compound
preparation
pharmaceutical formulations
Prior art date
1978-04-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB7912768A
Other versions

GB2018756A
(en

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Mediolanum Farmaceutici SpA

Original Assignee
Mediolanum Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1978-04-11
Filing date
1979-04-11
Publication date
1982-10-13

1978-04-11
Priority claimed from IT22175/78A
external-priority
patent/IT1095386B/en

1979-02-12
Priority claimed from IT2011179A
external-priority
patent/IT1166627B/en

1979-04-11
Application filed by Mediolanum Farmaceutici SpA
filed
Critical
Mediolanum Farmaceutici SpA

1979-10-24
Publication of GB2018756A
publication
Critical
patent/GB2018756A/en

1982-10-13
Application granted
granted
Critical

1982-10-13
Publication of GB2018756B
publication
Critical
patent/GB2018756B/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings

C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom

C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P11/00—Drugs for disorders of the respiratory system

A61P11/08—Bronchodilators

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P11/00—Drugs for disorders of the respiratory system

A61P11/10—Expectorants

GB7912768A
1978-04-11
1979-04-11
2-(2-thenoylthio)-propionylglycine: method for its preparation and pharmaceutical formulations containing said compound

Expired

GB2018756B
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

IT22175/78A

IT1095386B
(en)

1978-04-11
1978-04-11

2- (2-TENCILTIO) -PROPIONYLGLYCIN, METHOD FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT

IT2011179A

IT1166627B
(en)

1979-02-12
1979-02-12
2-2-Thenoyl-thio-propionyl-glycine – prepd. by reaction of thenoyl chloride with 2-mercapto-propionyl-glycine, is used to treat hepatopathy

Publications (2)

Publication Number
Publication Date

GB2018756A

GB2018756A
(en)

1979-10-24

GB2018756B
true

GB2018756B
(en)

1982-10-13

Family
ID=26327401
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB7912768A
Expired

GB2018756B
(en)

1978-04-11
1979-04-11
2-(2-thenoylthio)-propionylglycine: method for its preparation and pharmaceutical formulations containing said compound

Country Status (16)

Country
Link

US
(1)

US4242354A
(en)

JP
(1)

JPS5910673B2
(en)

AR
(1)

AR219379A1
(en)

AT
(1)

AT374194B
(en)

CA
(1)

CA1121825A
(en)

CH
(1)

CH639380A5
(en)

DE
(1)

DE2913211C2
(en)

DK
(1)

DK148117C
(en)

ES
(1)

ES479423A1
(en)

FR
(1)

FR2422657A1
(en)

GB
(1)

GB2018756B
(en)

IE
(1)

IE47946B1
(en)

LU
(1)

LU81132A1
(en)

NL
(1)

NL7902700A
(en)

NO
(1)

NO149312C
(en)

SE
(1)

SE444940B
(en)

Cited By (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4393053A
(en)

1981-02-02
1983-07-12
Refarmed S.A.
Thiolic derivatives or erythromycin having therapeutic activity and pharmaceutical compositions containing them

Families Citing this family (18)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

IT1149884B
(en)

*

1980-06-03
1986-12-10
Btb Ind Chimica

PROCEDURE FOR THE PREPARATION OF N- (2-TENOIL) TIOPROPIONIL) -GLYCIN

IT1148890B
(en)

*

1980-07-22
1986-12-03
Neopharmed Spa

TEONYL TIOPROPIONYL GLYCIN DERIVATIVE AND PROCEDURE FOR ITS PREPARATION

US4415681A
(en)

*

1980-10-23
1983-11-15
Ford Motor Company
Stabilized crosslinked dispersion

IT1143209B
(en)

*

1981-07-02
1986-10-22
Sigma Tau Ind Farmaceuti

2-TENOILMERCAPTOPROPIONYL GLYCIN ESTERS WITH HYDROXYBENZEN REPLACED PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

IE52884B1
(en)

*

1981-05-11
1988-03-30
Sigma Tau Ind Farmaceuti
2-methoxyphenyl esters of n-substituted amino acids, their preparation and pharmaceutical use

FR2521146B1
(en)

*

1983-02-02
1985-10-25
Sigma Tau Ind Farmaceuti

THEROLIC DERIVATIVES OF ERYTHROMYCIN WITH THERAPEUTIC ACTIVITY, PREPARATION METHOD, AND PHARMACEUTICAL PRODUCTS IN WHICH THEY APPEAR

IT1212723B
(en)

*

1983-03-23
1989-11-30
Medea Res Srl

Derivative of thiolactic acid for bronchosecretogenic activity.

JPS59191971U
(en)

*

1983-06-08
1984-12-20
有限会社 沢田久商店

pillow

JPS60152786U
(en)

*

1984-03-21
1985-10-11
三協アルミニウム工業株式会社

Sash frame removal device

US4595700A
(en)

*

1984-12-21
1986-06-17
G. D. Searle & Co.
Thiol based collagenase inhibitors

DE3770433D1
(en)

*

1987-02-05
1991-07-04
Caber Farmaceutici

4-OXO-1,3-BENZODIOXANE DERIVAT.

JPS63199669U
(en)

*

1987-05-22
1988-12-22

US6192882B1
(en)

*

1997-02-24
2001-02-27
Aradigm Corporation
Formulation and devices for monitoring the efficacy of the delivery of aerosols

US6349719B2
(en)

1997-02-24
2002-02-26
Aradigm Corporation
Formulation and devices for monitoring the efficacy of the delivery of aerosols

TWI598347B
(en)

2009-07-13
2017-09-11
基利科學股份有限公司
Apoptosis signal-regulating kinase inhibitors

AU2011272782B2
(en)

*

2010-07-02
2014-11-27
Gilead Sciences, Inc.
Apoptosis signal-regulating kinase inhibitors

CN106008456A
(en)

*

2016-06-27
2016-10-12
山东川成医药股份有限公司
Preparation method of stepronin

WO2022250957A2
(en)

*

2021-05-10
2022-12-01
Altibio, Inc.
Thioester prodrugs for the treatment of renal anomalies

Family Cites Families (4)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US2510773A
(en)

*

1946-05-18
1950-06-06
Sterling Drug Inc
Process for preparing a tertiary amino-alkyl thiol-ester hydrochloride

US2632735A
(en)

*

1951-03-01
1953-03-24
Standard Oil Dev Co
Lubricating oil additives

US2669564A
(en)

*

1951-03-17
1954-02-16
Sterling Drug Inc
Tertiary-aminoalkyl 4-amino-2-alkoxy-thiolbenzoates and their preparation

FR2338701A1
(en)

*

1976-01-23
1977-08-19
Blum Jean

NEW DERIVATIVES OF CYSTEINE

1979

1979-03-26
CA
CA000324110A
patent/CA1121825A/en
not_active
Expired

1979-03-27
FR
FR7907633A
patent/FR2422657A1/en
active
Granted

1979-04-03
DE
DE2913211A
patent/DE2913211C2/en
not_active
Expired

1979-04-04
US
US06/026,933
patent/US4242354A/en
not_active
Expired – Lifetime

1979-04-04
AT
AT0249879A
patent/AT374194B/en
not_active
IP Right Cessation

1979-04-04
CH
CH318279A
patent/CH639380A5/en
not_active
IP Right Cessation

1979-04-05
AR
AR276092A
patent/AR219379A1/en
active

1979-04-05
NL
NL7902700A
patent/NL7902700A/en
not_active
Application Discontinuation

1979-04-06
SE
SE7903105A
patent/SE444940B/en
not_active
IP Right Cessation

1979-04-09
LU
LU81132A
patent/LU81132A1/en
unknown

1979-04-09
ES
ES479423A
patent/ES479423A1/en
not_active
Expired

1979-04-10
NO
NO791205A
patent/NO149312C/en
unknown

1979-04-11
DK
DK153179A
patent/DK148117C/en
not_active
IP Right Cessation

1979-04-11
GB
GB7912768A
patent/GB2018756B/en
not_active
Expired

1979-04-11
JP
JP54044827A
patent/JPS5910673B2/en
not_active
Expired

1979-08-08
IE
IE788/79A
patent/IE47946B1/en
not_active
IP Right Cessation

Cited By (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4393053A
(en)

1981-02-02
1983-07-12
Refarmed S.A.
Thiolic derivatives or erythromycin having therapeutic activity and pharmaceutical compositions containing them

Also Published As

Publication number
Publication date

JPS54141761A
(en)

1979-11-05

NO149312C
(en)

1984-03-28

AT374194B
(en)

1984-03-26

GB2018756A
(en)

1979-10-24

IE790788L
(en)

1979-10-11

SE444940B
(en)

1986-05-20

FR2422657B1
(en)

1981-10-23

ATA249879A
(en)

1983-08-15

LU81132A1
(en)

1979-06-19

DK153179A
(en)

1979-10-12

DE2913211A1
(en)

1979-10-25

CH639380A5
(en)

1983-11-15

DK148117C
(en)

1985-08-26

NL7902700A
(en)

1979-10-15

IE47946B1
(en)

1984-07-25

JPS5910673B2
(en)

1984-03-10

NO149312B
(en)

1983-12-19

FR2422657A1
(en)

1979-11-09

US4242354A
(en)

1980-12-30

CA1121825A
(en)

1982-04-13

DK148117B
(en)

1985-03-11

DE2913211C2
(en)

1982-05-06

NO791205L
(en)

1979-10-12

AR219379A1
(en)

1980-08-15

ES479423A1
(en)

1979-11-01

SE7903105L
(en)

1979-10-12

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2-(2-thenoylthio)-propionylglycine: method for its preparation and pharmaceutical formulations containing said compound

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Legal Events

Date
Code
Title
Description

1999-05-05
PE20
Patent expired after termination of 20 years

Effective date:
19990410

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